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Scientific research

Established in Australia in 2010, ProPlenish conducts clinical studies, scientific research and testing in the field of collagen. Cutting edge scientific information is used in the research and development of ProPlenish products. The results from ongoing research allows ProPlenish to deliver to our customers:

+ The highest grade marine collagens in the world
+ The safety and certification of all products
+ The most bioavailable (fastest acting and greatest absorption) products on the market, both in Australia and internationally.

ProPlenish consults highly qualified leaders and experts in their fields; which include Professors, Biological scientists, Food scientists, Dietitians, Nutritionists, Dermatologists, University Researchers and Collagen experts.

We guarantee 100% that there is no animal testing done in our research and we conduct all of our studies on human subjects. We also guarantee our products are derived from wild caught deep-sea fish from pristine waters using sustainable fishing methods. Our laboratory testing confirms our products are pure and safe for consumption.

SCIENTIFIC STUDIES - COLLAGEN EFFECTS ON THE SKIN

91% increase in skin hydration and resilience in just 2 months

A 2008 study in Tokyo of 33 women aged 40-59 who took Hydrolyzed Collagen daily for 2 months showed a 91% increase in skin hydration and resilience (2).

Skin dryness and scaling reduced by 76% in 12 weeks

Significantly improves crow’s feet and overall facial ageing

Increases skin smoothness and hydration with less furrowing in 12 weeks

Reduction in age-related changes to the skin

70-80% of women are able to observe the effects of collagen ingestion on the skin

Higher skin elasticity and moisture after 8 weeks

Increased water content found in skin after just 6 weeks

Collagen ingestion stimulates natural collagen

Hydrolysed collagen improved dry and rough skin in 6 weeks

Improvements found in skin function and hydration after regular Collagen ingestion

Enhances the formation of and increases the density of collagen fibrils

Increases water absorbing capacity of the skin

May improve the mechanical strength of the skin

Replenishing collagen levels is needed to prevent skin ageing

Sun damaged skin showed significant improvements in thickness and elasticity

Findings showed collagen suppressed UV-B-induced skin damage and photoaging

Scientific data shows the oral intake of hydrolysed collagen may help to rejuvenate the skin and reduce signs of ageing

SCIENTIFIC STUDIES - COLLAGEN EFFECTS ON HAIR & NAILS

Increase of up to 49% in hair diameter after 3 months

A study by the Department of Pharmacology at the University of Milan, Italy, showed that the activity of hair follicles was – directly or indirectly – increased by the consumption of collagen. Results taken from patients after a three-month treatment showed an increase in hair diameter of up to 49% in some cases, with an average increase of 35% (14).

Thickness and strength of hair increases significantly after just 62 days

Significantly increases the hardness of fingernails

Improved nail defects in 80% of patients

SCIENTIFIC STUDIES - COLLAGEN EFFECTS ON MUSCLES & JOINTS

Improved body composition with increased muscle strength, tone and fat loss

A study on Collagen supplementation in combination with resistance training showed that Collagen improved body composition by increasing muscle strength and tone and the loss in fat. (17)

Preserves lean body mass (muscle tone)

Joint pain reduced in athletes

Improvement in osteoarthritis knee joint comfort

References

1. Kantor, I et al. 2002. Results of a Study Evaluating the Use of a Dietary Supplement Formula in the Management of Age-Related Skin Changes in Women with Moderate to Severe Wrinkling of the Periorbital Area. Journal of the American Nutraceutical Asscociation. Vol 5, No.2.

2. SOUKEN study 2008, Tokyo Japan: two month study hydrolyzed collagen.

3. DERMSCAN study, 2008, Lyon France. Cutaneous properties of hydrolyzed collagen.

4. Tanaka et al. Effects of collagen peptide ingestion on UV-B-induced skin damage. Biosci Biotechnol Biochem 73:930-932 (2009).

5. Matsuda, N.; Koyama, Y., Hosaka, Y., Ueda, H., Watanabe, T., Araya, T., Irie, S. and Takehana K. (2006). “Effects of ingestion of collagen peptide on collagen fibrils and glycosaminoglycans in the dermis”. Journal of nutrition vitaminology 52: 211-215.

6. Sumada E, Hirota A et al.: The effect of oral ingest of collagen peptide on skin hydration and biochemical data on blood. J. Nutri Food 7, (2004) 1-8

7. Morganti P, Randazzo S, Bruno C: Oral treatment of skin dryness. Cosmet Toilet. 103 (1988) 77-80

8. Koyama. Effects of collagen peptide ingestion on the skin. Shokuhin-To-Kaihatsu 44:10-12 (2009) (in Japanese).

9. Rousselot Publication, 2009. Hydrolyzed Collagen and Skin Health 2009 clinical studies results.

10. Eskelinin, A. and Santalahti, J. (1992) Special Natural cartilage polysaccharides for the treatment of sun-damaged skin in females. J Int Med Res; 20(2): 99 – 105

11. Proksch et al. (2014) Oral Supplementation of Specific Collagen Peptides Has beneficial Effects on Human Skin Physiology: A Double Blind, Placebo-Controlled Study. Skin Pharmacol Physiol 2014; 27:47:47 – 55

12. Zague et al. (2011) Collagen hydrolysate intake increases skin collagen expression and suppresses matrix metalloproteinase 2 activity. Journal of Medicinal Food 14 (6) 2011, 618–624

13. Matsumoto, H. et al. (2006) Clinical effect of fish type I collagen hydrolysate on skin properties. ITE Lett. 7. 386 – 390

14. Ohara H et al. (2010) Collagen-derived dipeptide, proline-hydroxyproline, stimulates cell proliferation and hyaluronic acid synthesis in cultured human dermal fibroblasts. The Journal of Dermatology Volume 37, Issue 4, pages 330–338.

15. Clark KL et al. (2008) 24-Week study on the use of collagen hydrolysate as a dietary supplement in athletes with activity-related joint pain. Current Medical Research and Opinion Vol. 24, No. 5, 2008, 1485–1496

16. Benito-Ruiz P et al. (2009) Randomized controlled trial on the efficacy and safety of a food ingredient, collagen hydrolysate, for improving joint comfort. Int J Food Sci Nutr; 60 Suppl 2:99-113.

17. Zdzieblik, D., Oesser, S., Baumstark, M. W., Gollhofer, A., & König, D. (2015). Collagen peptide supplementation in combination with resistance training improves body composition and increases muscle strength in elderly sarcopenic men: a randomised controlled trial. British Journal of Nutrition, 114(08), 1237-1245.

18. Hays, N. P., Kim, H., Wells, A. M., Kajkenova, O., & Evans, W. J. (2009). [Effects of whey and fortified collagen hydrolysate protein supplements on nitrogen balance and body composition in older women (www.ncbi.nlm.nih.gov/pubmed/19465192). Journal of the American Dietetic Association, 109(6), 1082-1087.

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